A perturbation approach to characterize absorptive inclusions in diffusing media by time-resolved contrast measurements
Year: 2004
Authors: Esposito R., De Nicola S., Lepore M., Delfino I., Indovina P.L.
Autors Affiliation: Dipartimento di Fisica, Università ‘Federico II’, Compl. Univ. Montesantangelo,
Via Cintia, 80126 Napoli, Italy;
Istituto Nazionale di Fisica della Materia, Unità di Napoli, Napoli, Italy;
Istituto di Cibernetica del CNR ‘E Caianiello’, Comprensorio A Olivetti, Via Campi Flegrei 34, 80078 Pozzuoli, Italy;
Dipartimento di Medicina Sperimentale, Seconda Università di Napoli, Italy
Biophysics and Nanoscience Centre, INFM, Environmental Science Department,
Università di Tuscia, Italy
Abstract: Time-resolved measurements of ultrashort light pulses transmitted through turbid scattering media have been performed to determine the possibilities and the limitations of a first-order perturbation approach to recover the absorption coefficient of different tissue-like cylindrical absorptive phantoms. The model accounts for the effect of a spatially varying absorption coefficient of an inclusion on the time-resolved transmittance. We have determined the absorption coefficient of the inhomogeneities located at the midplane of a scattering cell by fitting the diffusion approximation-based perturbation model to the experimental time-resolved contrast measurements. The accuracy of the model predictions is discussed. An error analysis of the fitting procedure is also presented.
Journal/Review: JOURNAL OF OPTICS A-PURE AND APPLIED OPTICS
Volume: 6 (7) Pages from: 736 to: 741
KeyWords: biological media; diffusion; scattering; time resolved; ultrashort pulsesDOI: 10.1088/1464-4258/6/7/013Citations: 7data from “WEB OF SCIENCE” (of Thomson Reuters) are update at: 2024-04-28References taken from IsiWeb of Knowledge: (subscribers only)Connecting to view paper tab on IsiWeb: Click hereConnecting to view citations from IsiWeb: Click here