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Author: Costantini Irene 

1) Fiber enhancement and 3D orientation analysis in label-free two-photon fluorescence microscopy in SCIENTIFIC REPORTS
By: Sorelli Michele; Costantini Irene; Bocchi Leonardo; Axer Markus; Pavone Francesco Saverio; Mazzamuto Giacomo Year: 2023 (Cit.: 0 DOI: 10.1038/s41598-023-30953-w)

2) 3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy in COMMUNICATIONS BIOLOGY
By: Pesce Luca; Scardigli Marina; Gavryusev Vladislav; Laurino Annunziatina; Mazzamuto Giacomo; Brady Niamh; Sancataldo Giuseppe; Silvestri Ludovico; Destrieux Christophe; Hof Patrick R.; Costantini Irene; Pavone Francesco S. Year: 2022 (Cit.: 0 DOI: 10.1038/s42003-022-03390-0)

3) Autofluorescence enhancement for label‑free imaging of myelinated fibers in mammalian brains in SCIENTIFIC REPORTS
By: Costantini I., Baria E., Sorelli M., Matuschke F., Giardini F., Menzel M., Mazzamuto G., Silvestri L., Cicchi R., Amunts K., Axer M., Pavone F.S. Year: 2021 (Cit.: 16 DOI: 10.1038/s41598-021-86092-7)

4) Comparison of Different Tissue Clearing Methods for Three-Dimensional Reconstruction of Human Brain Cellular Anatomy Using Advanced Imaging Techniques in FRONTIERS IN NEUROANATOMY
By: Scardigli M., Pesce L., Brady N., Mazzamuto G., Gavryusev V., Silvestri L., Hof PR., Destrieux C., Costantini I., Pavone FS. Year: 2021 (Cit.: 0 DOI: 10.3389/fnana.2021.752234)

5) Large-scale, cell-resolution volumetric mapping allows layer-specific investigation of human brain cytoarchitecture in BIOMEDICAL OPTICS EXPRESS
By: Costantini I., Mazzamuto G., Roffilli M., Laurino A., Castelli FM., Neri M., Lughi G., Simonetto A., Lazzeri E., Pesce L., Destrieux C., Silvestri L., Conti V., Guerrini R., Pavone FS Year: 2021 (Cit.: 12 DOI: 10.1364/BOE.415555)

6) Universal autofocus for quantitative volumetric microscopy of whole mouse brains in NATURE METHODS
By: Silvestri L., Mullenbroich MC., Costantini I., Di Giovanna AP., Mazzamuto G., Franceschini A., Kutra D., Kreshuk A., Checcucci C., Toresano LO., Frasconi P., Sacconi L., Pavone FS. Year: 2021 (Cit.: 25 DOI: 10.1038/s41592-021-01208-1)

7) Exploring the human cerebral cortex using confocal microscopy in PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
By: Pesce Luca; Laurino Annunziatina; Scardigli Marina; Yang Jiarui; Boas David A.; Hof Patrick R.; Destrieux Christophe; Costantini Irene; Pavone Francesco Saverio Year: 2021 (Cit.: 8 DOI: 10.1016/j.pbiomolbio.2021.09.001)

8) Towards a clearer view of sympathetic innervation of cardiac and skeletal muscles in PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
By: Di Bona A., Vita V., Costantini I., Zaglia T. Year: 2020 (Cit.: 18 DOI: 10.1016/j.pbiomolbio.2019.07.003)

9) Dissecting Neuronal Activation on a Brain-Wide Scale With Immediate Early Genes in FRONTIERS IN NEUROSCIENCE
By: Franceschini A., Costantini I., Pavone FS., Silvestri L. Year: 2020 (Cit.: 24 DOI: 10.3389/fnins.2020.569517)

10) 3D imaging and morphometry of the heart capillary system in spontaneously hypertensive rats and normotensive controls in SCIENTIFIC REPORTS
By: Olianti C., Costantini I., Giardini F., Lazzeri E., Crocini C., Ferrantini C., Pavone FS., Camici PG., Sacconi L. Year: 2020 (Cit.: 13 DOI: 10.1038/s41598-020-71174-9)

11) Toward a High-Resolution Reconstruction of 3D Nerve Fiber Architectures and Crossings in the Brain Using Light Scattering Measurements and Finite-Difference Time-Domain Simulations in PHYSICAL REVIEW X
By: Menzel M., Axer M., De Raedt H., Costantini I., Silvestri L., Pavone FS., Amunts K., Amunts K., Michielsen K. Year: 2020 (Cit.: 17 DOI: 10.1103/PhysRevX.10.021002)

12) In-vivo and ex-vivo optical clearing methods for biological tissues: review in BIOMEDICAL OPTICS EXPRESS
By: Costantini I., Cicchi R., Silvestri L., Vanzi F., Pavone F.S. Year: 2019 (Cit.: 103 DOI: 10.1364/BOE.10.005251)

13) Cardiac sympathetic innervation network shapes the myocardium by locally controlling cardiomyocyte size through the cellular proteolytic machinery in JOURNAL OF PHYSIOLOGY-LONDON
By: Pianca N., Di Bona A., Lazzeri E., Costantini I., Franzoso M., Prando V., Armani A., Rizzo S., Fedrigo M., Angelini A., Basso C., Pavone FS., Rubart M., Sacconi L., Zaglia T., Mongillo M. Year: 2019 (Cit.: 32 DOI: 10.1113/JP276200)

14) Whole-Brain Vasculature Reconstruction at the Single Capillary Level (vol 8, 12573, 2018) in SCIENTIFIC REPORTS
By: Di Giovanna AP., Tibo A., Silvestri L., Mullenbroich MC., Costantini I., Allegra Mascaro AL., Sacconi L., Frasconi P., Pavone FS. Year: 2019 (Cit.: 0 DOI: 10.1038/s41598-019-42216-8)

15) Three-dimensional analysis of human brain cytoarchitectonics by means of a SWITCH/TDE-combined clearing method
By: Costantini I., Mazzamuto G., Laurino A., Lazzari E., Sacconi L., Neri M., Simonetto A., Ruffilli M., Silvestri L., Pavone FS. Year: 2019 (Cit.: 0)

16) Whole-Brain Vasculature Reconstruction at the Single Capillary Level in SCIENTIFIC REPORTS
By: Di Giovanna A.P., Tibo A., Silvestri L., Muellenbroich M.C., Costantini I., Allegra Mascaro A.L., Sacconi L., Frasconi P., Pavone F.S. Year: 2018 (Cit.: 77 DOI: 10.1038/s41598-018-30533-3)

17) Whole heart cytoarchitecture at sub-cellular resolution
By: Lazzeri E., Costantini I., Cannazzaro S., Ferrantini C., Mazzamuto G., Crocini C., Cerbai E., Poggesi C., Pavone FS., Sacconi L. Year: 2018 (Cit.: 0)

18) High-fidelity imaging in brain-wide structural studies using light-sheet microscopy in ENEURO
By: Müllenbroich M.C., Silvestri L., Di Giovanna A.P., Mazzamuto G., Costantini I., Sacconi L., Pavone F.S. Year: 2018 (Cit.: 11 DOI: 10.1523/ENEURO.0124-18.2018)

19) Towards a full volumetric atlas of cell-specific neuronal spatial organization in the entire mouse brain
By: Silvestri L., Di Giovanna A.P., Mazzamuto G., Leergard T., Orsini F., Costantini I., Bjaalie J., Frasconi P., Pavone F.S. Year: 2018 (Cit.: 0)

20) Software tools for efficient processing of high-resolution 3D images of macroscopic brain samples
By: Mazzamuto G., Silvestri L., Costantini I., Orsini F., Roffilli M., Frasconi P., Sacconi L., Pavone F.S. Year: 2018 (Cit.: 0)

21) 3D human brain digital istopatology
By: Costantini I., Mazzamuto G., Silvestri L., Neri M., Roffilli M., Conti V., Guerrini R., Sacconi L., Pavone F.S. Year: 2018 (Cit.: 0 DOI: 10.1364/BRAIN.2018.BF4C.1)

22) Automatic Segmentation of Neurons in 3D Samples of Human Brain Cortex
By: Mazzamuto G., Costantini I., Neri M., Roffilli M., Silvestri L., Pavone F.S. Year: 2018 (Cit.: 0)

23) Correlative polarized light imaging and two-photon fluorescence microscopy for 3D myelinated fibers reconstruction
By: Costantini I., Menzel M., Silvestri L., Schubert N., Axer M., Amunts K., Pavone F.S. Year: 2017 (Cit.: 0)

24) Fast, image-based autofocus system for high-resolution optical microscopy of whole mouse brains
By: Silvestri L., Müllenbroich M.C., Costantini I., Di Giovanna A.P., Sacconi L., Pavone F.S. Year: 2017 (Cit.: 0 DOI: 10.1364/BODA.2017.JTu4A.8)

25) Optimal staining and clearing protocol for whole mouse brain vasculature imaging with light-sheet microscopy
By: Di Giovanna A.P., Tibo A., Silvestri L., Muellenbroich M.C., Costantini I., Sacconi L., Frasconi P., Pavone F.S. Year: 2017 (Cit.: 0)

26) Clearing of fixed tissue: a review from a microscopist´s perspective in JOURNAL OF BIOMEDICAL OPTICS
By: Silvestri L., Costantini I., Sacconi L., Pavone F.S. Year: 2016 (Cit.: 102 DOI: 10.1117/1.JBO.21.8.081205)

27) Towards automated neuron tracing via global and local 3D image analysis
By: Acciai L., Costantini I., Pavone F.S., Conti V., Guerrini R., Soda P., Iannello G. Year: 2016 (Cit.: 0)

28) Combination of two-photon fluorescence microscopy and label-free near-infrared reflectance: A new complementary approach for brain imaging
By: Costantini I., Mascaro A.L.A., Margoni E., Iannello G., Bria A., Sacconi L., Pavone F.S. Year: 2016 (Cit.: 0 DOI: 10.1364/CANCER.2016.JW3A.23)

29) Label-free near-infrared reflectance microscopy as a complimentary tool for two-photon fluorescence brain imaging in BIOMEDICAL OPTICS EXPRESS
By: Allegra Mascaro A.L., Costantini I., Margoni E., Iannello G., Bria A., Sacconi L., Pavone F.S. Year: 2015 (Cit.: 13 DOI: 10.1364/BOE.6.004483)

30) A versatile clearing agent for multi-modal brain imaging in SCIENTIFIC REPORTS
By: Costantini I., Ghobril J.P., Di Giovanna A.P., Allegra Mascaro A. L., Silvestri L., Müllenbroich M.C., Onofri L., Conti V., Vanzi F., Sacconi L., Guerrini R., Markram H., Iannello G., Pavone F.S. Year: 2015 (Cit.: 183 DOI: 10.1038/srep09808)

31) Comprehensive optical and data management infrastructure for high-throughput light-sheet microscopy of whole mouse brains in NEUROPHOTONICS
By: Muellenbroich M.C., Silvestri L., Onofri L., Costantini I., Van’t Hoff M., Sacconi L., Iannello G., Pavone F.S. Year: 2015 (Cit.: 17 DOI: 10.1117/1.NPh.2.4.041404)

32) A versatile clearing agent for multi modal brain imaging in SCIENTIFIC REPORTS
By: Costantini I., Ghobril JP, Di Giovanna AP, Allegra Mascaro AL, Silvestri L, Mllenbroich MC, Onofri L, Conti V, Vanzi F, Sacconi L, Guerrini R, Markram H, Iannello G, Pavone FS Year: 2015 (Cit.: 0 DOI: 10.1038/srep09808)

33) Computer-based automatic identification of neurons in gigavoxel-sized 3D human brain images
By: Soda P., Acciai L., Cordelli E., Costantini I., Sacconi L., Pavone F.S., Conti V., Guerrini R., Frasconi P., Iannello G. Year: 2015 (Cit.: 0)

34) Whole brain optical imaging
By: Silvestri L., Allegra Mascaro A.L., Costantini I., Sacconi L., Pavone F.S. Year: 2015 (Cit.: 0 DOI: 10.1117/12.2087339)

35) A multi modal clearing method for brain imaging
By: Costantini I., Mascaro A.L.A., Di Giovanna A.P., Silvestri L., Müllenbroich M.C., Sacconi L., Pavone F.S. Year: 2015 (Cit.: 0 DOI: 10.1364/BRAIN.2015.BrM3B.2)

36) A new versatile clearing method for brain imaging
By: Costantini I., Di Giovanna A.P., Allegra Mascaro A.L., Silvestri L., Müllenbroich M.C., Sacconi L., Pavone F.S. Year: 2015 (Cit.: 0 DOI: 10.1117/12.2076908)

37) Multiphoton microscopy in brain imaging
By: Allegra Mascaro A.L., Silvestri L., Costantini I., Sacconi L., Maco B., Knott G.W., Pavone F.S. Year: 2015 (Cit.: 0 DOI: 10.1117/12.2084183)

38) A versatile new technique to clear mouse and human brain
By: Costantini I., Di Giovanna A.P., Mascaro A.L.A., Silvestri L., Müllenbroich M.C., Sacconi L., Pavone F.S. Year: 2015 (Cit.: 0 DOI: 10.1117/12.2184289)

39) Brain-wide charting of neuronal activation maps with cellular resolution
By: Silvestri L., Rudinskiy N., Paciscopi M., Müllenbroich M.C., Costantini I., Sacconi L., Frasconi P., Hyman B.T., Pavone F.S. Year: 2015 (Cit.: 0 DOI: 10.1364/BRAIN.2015.BrM3B.6)

40) Brain imaging from the nano- to the macro-scale
By: Silvestri L., Allegra Mascaro A.L., Costantini I., Sacconi L., Pavone F.S. Year: 2015 (Cit.: 0 DOI: 10.1109/NER.2015.7146760)

41) Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis in FRONTIERS IN MICROBIOLOGY
By: Rosentul D.C., Delsing C.E., Jaeger M., Plantinga T.S., Oosting M., Costantini I., Venselaar H., Joosten L.A.B., van der Meer J.W.M., Dupont B., Kullberg B.-J., Sobel J.D., Netea M.G. Year: 2014 (Cit.: 0 DOI: 10.3389/fmicb.2014.00483)

42) Micron-scale Resolution Optical Tomography of Entire Mouse Brains with Confocal Light Sheet Microscopy in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
By: Silvestri L., Bria A., Costantini I., Sacconi L., Peng H., Iannello G., Pavone F.S. Year: 2013 (Cit.: 17 DOI: 10.3791/50696)

43) Neural plasticity explored by correlative two-photon and electron/spim microscopy
By: Mascaro A.L.Allegra, Silvestri L., Costantini I., Sacconi L., Maco B., Knott G.W., Pavone F.S. Year: 2013 (Cit.: 0 DOI: 10.1117/12.2032505)

44) A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma in CARCINOGENESIS
By: Plantinga T.S., Costantini I., Heinhuis B., Huijbers A., Semango G., Kusters B., Netea M.G., Hermus A.R.M.M., Smit J.W.A., Dinarello C.A., Joosten L.A.B., Netea-Maier R.T. Year: 2013 (Cit.: 32 DOI: 10.1093/carcin/bgt092)