Differential absorption imaging for elemental analysis of thin samples using a soft laser-plasma X-ray source

Year: 2005

Authors: Laville S., Gizzi LA., Köster P., Labate L.

Autors Affiliation: CNR, IPCF, Intense Laser Irradiat Lab, I-56124 Pisa, Italy;
Ist Nazl Fis Nucl, Sez Pisa, Pisa, Italy;
Univ Pisa, Dipartimento Fis, Pisa, Italy

Abstract: The differential X-ray imaging technique is a powerful tool for the detection of small concentrations of contrast agents in samples, as demonstrated recently by many biological and medical applications using synchrotron radiation. In this paper, we present an implementation of this technique using a laser-plasma soft X-ray source combined with an X-ray imaging system based upon a spherically bent Bragg crystal. Using a test sample containing a solution of LiBr of known concentration, we demonstrate that the use of our table-top configuration is suitable to detect Br inside our sample via differential imaging at the L-2 edge of Br at 7.7684 Angstrom. (C) 2004 ElsevierB.V. All rights reserved.

Journal/Review: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT

Volume: 538 (1-3)      Pages from: 738  to: 746

KeyWords: synchrotron-radiation; medical applications; emission; angiography; resolution
DOI: 10.1016/j.nima.2004.09.004

Citations: 1
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